Cystic Fibrosis Institute

cysticfibrosisinstitute.org

   Advancing cystic fibrosis knowledge and care is a vital aspect of The Cystic Fibrosis
   Institute. CFI, in conjunction with The Cystic Fibrosis Center of Chicago, is active in the
   worldwide CF community and can offer clinical research studies that are testing the
   latest treatments for people with CF. By participating in independent studies, federally
   sponsored NIH research, or pharmaceutical-based multi-center clinical trials, CFI is
   helping to discover and develop new and more effective treatment strategies in order to
   improve the health of people with CF. Dr. Boas and his colleagues have published their
   research findings in many prestigious national and international medical journals.

cfi@wecare4lungs.com

"The Cystic Fibrosis Institute (CFI) was founded on the fundamental principle that
every person with cystic
fibrosis (CF) deserves the opportunity to realize his
or her full potential, to
lead as normal a life as
possible and, despite the
many obstacles they and
their families face, share
in the joys of life itself."

   - Quality Improvements In CF Health Care Delivery
   - Factors limiting Anaerobic Exercise
   - Exercise recommendations for CF
   - Parental attitudes about exercise
   - Energy metabolism during exercise
   - Exercise induced immune modulation
   - Vascular endothelial growth factor
   - CF Gene analysis and exercise
   - Breathing patterns during exercise

   - Growth Hormone Use
   - Inhalational Antibiotics—Aztreonam
   - Genetic Modifiers
   - Epidemiologic study of CF (Registry)
   - Stool elastase
   - CF Twins—Genetic Analysis
   - The Role of Zithromax in CF
   - CF and the RSV vaccine
   - Exercise, Cytokines, and Growth factors
   - Use of Pulmozyme in young children
   - CT and inflammatory markers in CF
   - Non tuberculous infection in CF
   - Inhaled Levaquin
   - Denufosol in CF
   - Tobramycin / Fosfomycin for Inhalation
   - Pancreatic Enzymes

Research presented at national and international meetings including:

American Thoracic Society

American College of Sports Medicine

North American Cystic Fibrosis Annual Meeting

North American Society Pediatric Exercise Medicine
American Academy of Pediatrics

   The Cystic Fibrosis Institute is committed to make available all therapies to people
   with CF whether already on the market or in research trials. The Clinical Trials Center
   is a means of overcoming barriers to research participation.

   The CFI Center for Clinical Trials provides individuals with CF the opportunity to
   participate in Phase II, III and IV clinical trials. The center’s staff have extensive
   experience in research sponsored by the National Institute of Health, the Cystic
   Fibrosis Foundation, and Pharmaceutical companies.

   Dr. Boas is a Board Certified Pediatric Pulmonologist and Associate Professor at
   Northwestern University Feinberg School of Medicine. As medical director of the
   center, he is personally responsible for oversight of all studies to ensure the safety
   to the participants. Some of the studies that he has conducted in CF include:

   Zithromax | RSV Vaccine | Pulmozyme | Pancreatic Enzymes | TOBI
                      Inhaled Aztreonam | Colistin | Inhaled Denufosol

   Nadia Yala and Karen Acker serve as Research Coordinators. Nadia has a medical
   degree from LaPerrine School of Medicine in Algeria. Prior to becoming involved
   in CF research, she worked as a cardiologist for over 15 years both in her own private
   practice and in a hospital setting.

   Karen has a BS degree in nursing from Calvin College in Grand Rapids, Michigan.
   She worked as a floor nurse for 7 years before shifting her focus to research and
   coordinating drug, device and interventional trials at Evanston and Northwestern
   Memorial Hospitals.

Barriers to participation in clinical research are commonplace. Do any of the
following sound familiar?

   - “I don’t want my child to miss school.”
   - “Let someone else do it.”
   - “Can’t I just get the medicine without
      being in the study?”
   - “I have to work.”
   - “I hate hospitals.”
   - “I’m lazy.”

   It is difficult for anyone to participate in
   clinical trials. The CFI Center for Clinical
   Trials understands these issues and is
   offering an unique program to enhance
   participation for all who qualify for study.

Specifically, the Center offers clinical trials with:

     1. Saturday and evening hours.
     2. Availability to anyone with CF who qualifies regardless of where clinical
       care is given.
     3. Dedicated and experienced research staff.
     4. Reimbursement for time and travel expenses.
     5. Study medications that are free to the participant.
     6. Warm and friendly environment without the hassles of traveling to a
            hospital.
     7. Easy parking.
     8. Convenient locations accessible by highways without city driving.

Our Address:
2401 Ravine Way, Suite 302, Glenview, Illinois 60025